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Results: The main disorders examined and treated via a gentle hormonal medication support and life style corrections by a pediatric gynecologist were: pubertas praecox - thelarche praecox and early menarche; dysfunctional juvenile metrorrhagia; central and peripheral endocrine disorders; eating disorders - anorexia mentalis and bulimia; obesity; excessive sport activities; autoimmune disorders, and others.

Normalization of the menstrual cycle was achieved while monitoring progress with a series of hormonal cytologies in a majority of patients.

In the late 1990s, periodontitis-atherosclerosis syndrome (PAS) was described and the number of articles devoted to PAS has increased every year.

Poor self-reported oral health (as a possible risk factor for periodontitis) and tooth loss (as a possible consequence of periodontitis) are positively associated with a coronary atherosclerotic burden [5].This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s).For a more detailed analysis, a 3-year period from 2013 to 2015 was chosen.Four hundred and fifty-two patients were investigated, many of them several times and for a period longer than the 3 years analyzed.

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